Periprosthetic joint infection (PJI) is a serious complication that can occur after joint replacement surgery. It involves the infection of the tissues and bone surrounding the artificial joint. While PJI is relatively rare, it can lead to significant complications and may require additional surgeries. Causes of Periprosthetic Joint Infection Contamination during surgery: Bacteria can enter the joint during the surgical procedure. Hematogenous spread: Bacteria can spread to the joint from another infected site in the body. Direct inoculation: The joint can become infected through a wound or puncture. Symptoms of Periprosthetic Joint Infection Pain and swelling: Persistent pain and swelling around the joint. Fever: A fever may indicate an infection. Redness and warmth: The skin around the joint may become red and warm to the touch. Drainage: Pus or other drainage may leak from the wound. Limited ...